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Tumor Fusion Gene Data Portal

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Laatst bijgewerkt: 2022-02-05 06:47:51

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Toegevoegd door: Nick Flower

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TCGA Fusion Gene Database - tumorfusions.org

Tumor Fusion Gene Data Portal. Table below summarizes the tumor types available across thirty three tumor types, as of July 2017. For more information, please read our Oncogene publication: The landscape and therapeutic relevance of cancer-associated transcript fusions.
Url: https://tumorfusions.org/
TCGA Fusion Gene Database - tumorfusions.org

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Toegevoegd door: Karen Eltakchi

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TumorFusions: an integrative resource for cancer ...

Gene fusion represents a class of molecular aberrations in cancer and has been exploited for therapeutic purposes. In this paper we describe TumorFusions, a data portal that catalogues 20 731 gene fusions detected in 9966 well characterized cancer samples and 648 normal specimens from The Cancer Genome Atlas (TCGA).
Url: https://pubmed.ncbi.nlm.nih.gov/29099951/
TumorFusions: an integrative resource for cancer ...

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Toegevoegd door: Glenn Poder

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FusionGDB: Fusion Gene annotation DataBase

FusionGDB is the Fusion Gene annotation DataBase, ... Furthermore, we identified 896 and 118 in-frame FGs not-retained their functional domains of tumor suppressor genes and DNA damage repair genes, respectively. On the other hand, we identified 6863 …
Url: https://ccsm.uth.edu/FusionGDB/index.html
FusionGDB: Fusion Gene annotation DataBase

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Toegevoegd door: Richard Lynch

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ChimerDB 4.0: an updated and expanded database of fusion genes

08-01-2020 · INTRODUCTION. Fusion genes continue to serve as an important source of biomarkers and therapeutic targets in various types of cancer. Since the groundbreaking discovery of BCR–ABL1 fusion gene in leukemia, numerous driver fusion alterations have been identified as druggable targets, including genes such as TMPRSS2, ALK, RET, FGFR3, ROS1 and …
Url: https://academic.oup.com/nar/article/48/D1/D817/5611671
ChimerDB 4.0: an updated and expanded database of fusion genes

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Toegevoegd door: Ste Sch

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Fusion Genes and RNAs in Cancer Development

04-02-2021 · 2. Biological Functions of Fusion Genes and RNAs. Solid tumors and hematopoietic malignancies often have highly complex, unstable genomes. Many gene fusions are random events caused by genetic instability or abnormal splicing machinery [39,40].These changes at the gene or RNA level are unlikely to result in functional nucleic acids or proteins, as they may …
Url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931065/
Fusion Genes and RNAs in Cancer Development

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Toegevoegd door: Evan Mahony

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TumorFusions: an integrative resource for cancer ...

04-01-2018 · Although the tumor fusion portal is currently built upon TCGA data, it is not bound to TCGA and expansion beyond TCGA is currently being scheduled. This includes but is not limited to pediatric cancers, in which fusion genes frequently are tumor initiating events, cancer cell lines available through the cancer cell line encyclopedia ( 31 ) and to integrate with published cancer …
Url: https://academic.oup.com/nar/article/46/D1/D1144/4584571
TumorFusions: an integrative resource for cancer ...

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Toegevoegd door: Rebecca Collits

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Portal towards Databases and Sites related to Genetics ...

TCGA Fusion gene Data Portal (MD Anderson Cancer Center Landscape of cancer-associated fusions using the Pipeline for RNA sequencing Data Analysis The gene fusions correspond to the Table 4 (tier 1 and 2) of the paper : The landscape and therapeutic relevance of cancer-associated transcript fusions. K Yoshihara et al. (2014) Oncogene, 1-10.
Url: http://atlasgeneticsoncology.org/extdef.html
Portal towards Databases and Sites related to Genetics ...

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Toegevoegd door: Halo Healthcare

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IMPACT web portal: oncology database integrating molecular ...

20-04-2018 · For drugs that target gene fusions, we extracted additional known gene fusions from ChimerDB and the Tumor Fusion Gene Data Portal . We then queried the drugs list against ClinicalTrials.gov to retrieve all drugs tested in cancer clinical trials. Through these steps, we collected 776 drugs, 1326 target genes and 435 target gene variants.
Url: https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-018-0350-1
IMPACT web portal: oncology database integrating molecular ...

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Toegevoegd door: D. Phillips

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PAX8–GLIS3 gene fusion is a pathognomonic genetic ...

04-07-2019 · The presence of the in-frame candidate fusion genes identified was also assessed across 33 cancer types in the tumor fusion gene data …
Url: https://www.nature.com/articles/s41379-019-0313-x
PAX8–GLIS3 gene fusion is a pathognomonic genetic ...

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Toegevoegd door: Oncoscholar

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Accessing TCGA data from GDC portal

Accessing TCGA data from GDC portal

Toegevoegd door: National Cancer Institute

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The GDC Data Portal - Video Guides to the Genomic Data Commons

The GDC Data Portal - Video Guides to the Genomic Data Commons

Toegevoegd door: Precision Health

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Genomic Data Commons GDC Data Portal

Genomic Data Commons GDC Data Portal

Toegevoegd door: Future omics Basic and Advanced Bioinformatics

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TCGA Part I

TCGA Part I

Toegevoegd door: Farhan Haq

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Cancer Genomics (Part 3): Easy guide to access RNA sequencing data of cancer (Example: Cbioportal)

Cancer Genomics (Part 3): Easy guide to access RNA sequencing data of cancer (Example: Cbioportal)

Toegevoegd door: Bioinformatics DotCa

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Gene Fusion and Rearrangments

Gene Fusion and Rearrangments

Toegevoegd door: National Human Genome Research Institute

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TCGA: Identification of Gene Fusions Using RNA Sequencing Data - Siyuan Zheng

TCGA: Identification of Gene Fusions Using RNA Sequencing Data - Siyuan Zheng

Toegevoegd door: Bioinformatics DotCa

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Gene Fusion Discovery

Gene Fusion Discovery

Toegevoegd door: Bioinformatics DotCa

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Gene Fusion Discovery

Gene Fusion Discovery

Toegevoegd door: JSU Bioinformatics

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COSMIC - Catalog Of Somatic Mutations In Cancer

COSMIC - Catalog Of Somatic Mutations In Cancer
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